Calcium Channel Ca<sub>V</sub>α<sub>1</sub> Splice Isoforms - Tissue Specificity and Drug Action
نویسندگان
چکیده
منابع مشابه
The impact of splice isoforms on voltage-gated calcium channel α1 subunits
Semi-conserved exon boundaries in members of the CACNA1 gene family result in recurring pre-mRNA splicing patterns. The resulting variations in the encoded pore-forming subunit of the voltage-gated calcium channel affect functionally significant regions, such as the vicinity of the voltage-sensing S4 segments or the intracellular loops that are important for protein interaction. In addition to ...
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ژورنال
عنوان ژورنال: Current Molecular Pharmacology
سال: 2015
ISSN: 1874-4672
DOI: 10.2174/1874467208666150507103215